They have their own record label Anjunabeats, which releases trance and progressive music, and they also host their own weekly radio show Group Therapy Radio. The group's tracks are regularly played by DJs around the world, including Armin van Buuren, Gareth Emery, Ferry Corsten, and Kyau & Albert.

On 19 October 2012 DJ Magazine announced the results of their annual Top 100 DJ Poll, with Above & Beyond placed at #8 in the world Jono Grant and Paavo Siljamäki met at the University of Westminster where they were both pursuing a degree in Electronic Engineering.

Having discovered a common mutual interest for electronic music, they decided to collaborate in writing music together. Following Paavo's suggestion, they set up the Anjunabeats label in the summer of 1999 with the release of their first single 'Volume One' under the alias Anjunabeats.

Initially, the Anjunabeats record label was founded as a medium to release their own music, however since the label acquired the same name as their production alias, they started to release music under different names, most notably as "Dirt Devils" and "Free State".

The original mix of 'Volume One', packaged with their 'Tease Dub Mix', received immediate attention in various dance clubs, and quickly gained support from superstar DJ's such as Pete Tong, Paul Oakenfold, Judge Jules and Paul van Dyk.

Following the success of 'Volume One' and a string of singles and remixes under their 'Free State' & 'Dirt Devils' alter egos, Marketing Director & Manager of the Warner Music Group Tony McGuinness, was alerted to the duo by his brother, Liam McGuinness.

Having been commissioned to remix Chakra's "Home" track, Tony McGuinness recruited Jono & Paavo to help him complete the remix. When the group was searching for a name to use for their Chakra remix, the inspiration came from a web page belonging to an American motivational trainer coincidentally named Jono Grant.

Jono had the poster stuck to his wall. The slogan used by the motivational trainer was "Above & Beyond", and they decided to use that as their name. Although the group was relatively unknown at the time, their remix of Chakra's Home was picked over remixes by Rob Searle and Tilt to be the A side mix, and after plays by Pete Tong on BBC Radio 1, it reached number one in the UK club charts.

In 2002 the team began their DJ career in Tokyo in front of 8,000 clubbers, on a bill featuring Ferry Corsten and DJ Tiësto. After a slow start to their DJ career, they are now considered headline acts and make regular appearances at some of the worlds biggest trance festivals and clubs including Creamfields and Godskitchen Global Gathering in the UK and Amnesia in Ibiza.

Furthermore, on 31 December 2007, Above & Beyond unofficially hosted the largest DJ gig ever on Barra Beach, Rio de Janeiro, where they reportedly played to an estimated 1 million people. In 2009, Above & Beyond also DJ'd at the official launch of Virgin Galactic's SpaceShipTwo.

The event took place in the Mojave Desert, and was hosted by Sir Richard Branson and attended by Arnold Schwarzenegger. The DJ set was secured after Above & Beyond's Buzz Aldrin-sampling club track "Buzz" was picked by Virgin to soundtrack the unveiling of the spaceship itself.

Above & Beyond have won the BBC Radio 1 Essential Mix of the Year twice in 2004 and 2011. They are the only people to have won Essential mix of the Year twice. Above & Beyond were ranked #4 in the DJ Mag top 100 poll from 2008 and 2009, having entered at #39 in 2004.

In 2010 and also in 2011, they placed #5 in the DJ Mag Top 100 Poll.